The measurement of serum ceruloplasmin generally follows two distinct approaches: functional activity assays and immunological quantification.
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Ceruloplasmin plays a dual role in human physiology. As a transport protein, it regulates the distribution of copper throughout the body. More critically, its ferroxidase activity facilitates the oxidation of ferrous iron (Fe2+) to ferric iron (Fe3+). This conversion is essential for loading iron onto transferrin, allowing for safe transport through the bloodstream. The measurement of serum ceruloplasmin generally follows two