The U.S. is unique in its treatment of DHEA as a supplement; most other developed nations regulate it as an anabolic steroid or a prescription drug. Regulation Status

: While oral DHEA is OTC in the U.S., some specific medical forms, such as the vaginal insert Intrarosa (prasterone) used for menopause symptoms, require a prescription.

: It is readily available in oral forms like capsules, tablets, and powders, as well as topical creams and gels.

; illegal to import without a prescription, and such imports are typically confiscated. European Union Generally banned for use in food and food supplements. Important Safety & Regulatory Considerations

: DHEA is a precursor to estrogen and testosterone. Experts recommend consulting a doctor before use, especially if you have a history of hormone-sensitive cancers (breast, ovarian, or prostate).