Furthermore, the lack of a pupil disrupts the flow of aqueous humor from the posterior chamber to the anterior chamber of the eye. This fluid blockage often provokes pupillary block and secondary angle-closure glaucoma, leading to dangerously high intraocular pressure that can destroy the optic nerve. Acorea - Definition, Meaning & Synonyms - Vocabulary.com

Acorea is a rare ophthalmological condition defined as the . Deriving from the Greek "a-" (without) and "kore" (pupil), this condition means light cannot pass properly through the iris to the retina.

This type is much less common and occurs later in life as a result of severe ocular trauma or chronic inflammatory diseases. Prolonged conditions like severe uveitis or advanced leprosy can cause the iris to fuse or become covered with thick, fibrotic scar tissue that completely obliterates the pupil. Clinical Challenges and Diagnosis

Acorea can be broadly categorized into two types: congenital and acquired.

The most immediate consequence of acorea is severe light deprivation. Because the eye cannot receive adequate visual stimuli, the brain fails to develop the neurological pathways necessary for clear sight. This invariably leads to dense stimulus-deprivation amblyopia (lazy eye).